Modeling Development and Disease with Organoids
Abstract
Recent advances in 3D culture technology allow embryonic and adult mammalian stem cells to exhibit their remarkable self-organizing properties, and the resulting organoids reflect key structural and functional properties of organs such as kidney, lung, gut, brain and retina. Organoid technology can therefore be used to model human organ development and various human pathologies 'in a dish." Additionally, patient-derived organoids hold promise to...
Paper Details
Title
Modeling Development and Disease with Organoids
Published Date
Jun 1, 2016
Journal
Volume
165
Issue
7
Pages
1586 - 1597
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