Pharmacological Intervention in Type 2 Diabetes Mellitus - A Pathophysiologically Reasoned Approach?

Introduction: In recent years, numerous pharmacological approaches for the treatment of type 2 diabetes mellitus (T2DM) have become available. While all of them have proven blood glucose-lowering effects, identifying the most beneficial drug or drug combination for the treatment of an individual patient has become an increasing challenge. Several guidelines attempt to provide decision criteria based on clinical characteristics and comorbidities...