Peroxidation of linolenic acid--catalysis by transition metal ions.

Numerous studies have demonstrated that several indices of oxidative damage are enhanced in target tissues of rodents exposed to various transition metal ions. Whether or not these indices represent primary or secondary effects are not known, since tissues injured by other mechanisms are susceptible to an increased rate of lipid peroxidation (LP). In the current study, the reaction mixtures (metal ions with linolenic acid) were preincubated at...