Match!

Nothing Boring About Boron

Lara Pizzorno3
Estimated H-index: 3
Abstract
The trace mineral boron is a micronutrient with diverse and vitally important roles in metabolism that render it necessary for plant, animal, and human health, and as recent research suggests, possibly for the evolution of life on Earth. As the current article shows, boron has been proven to be an important trace mineral because it (1) is essential for the growth and maintenance of bone; (2) greatly improves wound healing; (3) beneficially impacts the body’s use of estrogen, testosterone, and vitamin D; (4) boosts magnesium absorption; (5) reduces levels of inflammatory biomarkers, such as high-sensitivity C-reactive protein (hs-CRP) and tumor necrosis factor α (TNF-α); (6) raises levels of antioxidant enzymes, such as superoxide dismutase (SOD), catalase, and glutathione peroxidase; (7) protects against pesticide-induced oxidative stress and heavy-metal toxicity; (8) improves the brains electrical activity, cognitive performance, and short-term memory for elders; (9) influences the formation and activity of key biomolecules, such as S-adenosyl methionine (SAM-e) and nicotinamide adenine dinucleotide (NAD+); (10) has demonstrated preventive and therapeutic effects in a number of cancers, such as prostate, cervical, and lung cancers, and multiple and non-Hodgkin’s lymphoma; and (11) may help ameliorate the adverse effects of traditional chemotherapeutic agents. In none of the numerous studies conducted to date, however, do boron’s beneficial effects appear at intakes > 3 mg/d. No estimated average requirements (EARs) or dietary reference intakes (DRIs) have been set for boron—only an upper intake level (UL) of 20 mg/d for individuals aged ≥ 18 y. The absence of studies showing harm in conjunction with the substantial number of articles showing benefits support the consideration of boron supplementation of 3 mg/d for any individual who is consuming a diet lacking in fruits and vegetables or who is at risk for or has osteopenia; osteoporosis; osteoarthritis (OA); or breast, prostate, or lung cancer.
  • References (2)
  • Citations (26)
Cited By26
Newest
#1Monireh Sadat Motaharifard (Tehran University of Medical Sciences)H-Index: 1
#2Mohammad Effatpanah (Tehran University of Medical Sciences)H-Index: 3
Last.Fatemeh Nejatbakhsh (Tehran University of Medical Sciences)H-Index: 4
view all 7 authors...
#1Eugeniy Demianenko (NASU: National Academy of Sciences of Ukraine)H-Index: 1
#2Alexey V. Rayevsky (NASU: National Academy of Sciences of Ukraine)H-Index: 1
Last.José G. Trujillo-Ferrara (IPN: Instituto Politécnico Nacional)H-Index: 11
view all 4 authors...
#1Agata Lapa (FAU: University of Erlangen-Nuremberg)H-Index: 1
#2Mark CresswellH-Index: 2
Last.Aldo R. Boccaccini (FAU: University of Erlangen-Nuremberg)H-Index: 82
view all 4 authors...
#1Ruya Kuru (Marmara University)H-Index: 2
#2Sahin Yilmaz (Yeditepe University)H-Index: 2
Last.Fikrettin Sahin (Yeditepe University)H-Index: 34
view all 5 authors...
#1Riccardo Innocenti Malini (Empa: Swiss Federal Laboratories for Materials Science and Technology)H-Index: 1
#2Jessica Lesage (Empa: Swiss Federal Laboratories for Materials Science and Technology)
Last.Fabrizio Spano (Empa: Swiss Federal Laboratories for Materials Science and Technology)H-Index: 10
view all 6 authors...
View next paperBoron-Containing Compounds as Preventive and Chemotherapeutic Agents for Cancer