Interplay between Metabolism and Epigenetics: A Nuclear Adaptation to Environmental Changes
Abstract
The physiological identity of every cell is maintained by highly specific transcriptional networks that establish a coherent molecular program that is in tune with nutritional conditions. The regulation of cell-specific transcriptional networks is accomplished by an epigenetic program via chromatin-modifying enzymes, whose activity is directly dependent on metabolites such as acetyl-coenzyme A, S-adenosylmethionine, and NAD+, among others....
Paper Details
Title
Interplay between Metabolism and Epigenetics: A Nuclear Adaptation to Environmental Changes
Published Date
Jun 2, 2016
Journal
Volume
62
Issue
5
Pages
695 - 711
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Notes
History