The application of genome editing in studying hearing loss
Abstract
Targeted genome editing mediated by clustered, regularly interspaced, short palindromic repeat (CRISPR)/CRISPR-associated nuclease 9 (Cas9) technology has emerged as one of the most powerful tools to study gene functions, and with potential to treat genetic disorders. Hearing loss is one of the most common sensory disorders, affecting approximately 1 in 500 newborns with no treatment. Mutations of inner ear genes contribute to the largest...
Paper Details
Title
The application of genome editing in studying hearing loss
Published Date
Sep 1, 2015
Journal
Volume
327
Pages
102 - 108
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