Molecular Genetics of Atrial Fibrillation
Abstract
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia. There is genetic predisposition for the development of AF. Recently, by linkage analysis, several loci have been mapped for monogenetic AF, which include 11p15.5, 21q22, 17q, 7q35-36, 5p13, 6q14-16, and 10q22. Some of these loci encode for subunits of potassium channels (KCNQ1, KCNE2, KCNJ2 and KCNH2 genes), and the remaining are yet unidentified. All of the mutations are...
Paper Details
Title
Molecular Genetics of Atrial Fibrillation
Published Date
Dec 1, 2008
Journal
Volume
24
Issue
4
Pages
177 - 190
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