Rhesus monkey model of liver disease reflecting clinical disease progression and hepatic gene expression analysis
Abstract
Alcoholic liver disease (ALD) is a significant public health issue with heavy medical and economic burdens. The aetiology of ALD is not yet completely understood. The development of drugs and therapies for ALD is hampered by a lack of suitable animal models that replicate both the histological and metabolic features of human ALD. Here, we characterize a rhesus monkey model of alcohol-induced liver steatosis and hepatic fibrosis that is...
Paper Details
Title
Rhesus monkey model of liver disease reflecting clinical disease progression and hepatic gene expression analysis
Published Date
Oct 7, 2015
Journal
Volume
5
Issue
1
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