Type 3 Muscarinic Receptors Contribute to Clearance of Citrobacter rodentium
Abstract
The role of muscarinic receptors in mucosal homeostasis, response to enteric pathogens, and modulation of immune cell function is undefined.The contribution of type 3 muscarinic receptors (M3R) to mucosal homeostasis within the colon and host defense against Citrobacter rodentium was determined in uninfected and C. rodentium-infected WT and M3R-deficient (Chrm3) mice. In addition, WT and Chrm3 bone marrow-derived macrophages were studied to...
Paper Details
Title
Type 3 Muscarinic Receptors Contribute to Clearance of Citrobacter rodentium
Published Date
Aug 1, 2015
Journal
Volume
21
Issue
8
Pages
1860 - 1871
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