DNA End Resection: Facts and Mechanisms.

Volume: 14, Issue: 3, Pages: 126 - 130
Published: Jun 1, 2016
Abstract
DNA double-strand breaks (DSBs), which arise following exposure to a number of endogenous and exogenous agents, can be repaired by either the homologous recombination (HR) or non-homologous end-joining (NHEJ) pathways in eukaryotic cells. A vital step in HR repair is DNA end resection, which generates a long 3′ single-stranded DNA (ssDNA) tail that can invade the homologous DNA strand. The generation of 3′ ssDNA is not only essential for HR...
Paper Details
Title
DNA End Resection: Facts and Mechanisms.
Published Date
Jun 1, 2016
Volume
14
Issue
3
Pages
126 - 130
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