Peri-alloHCT IL-33 administration expands recipient T-regulatory cells that protect mice against acute GVHD
Abstract
Key Points Peri-alloHCT IL-33 delivery prevents acute GVHD through MAPK-dependent expansion of radiation-resistant recipient ST2+ Tregs. IL-33–expanded Tregs regulate myeloid cell differentiation and activation, and limit effector T-cell accumulation in GVHD-target...
Paper Details
Title
Peri-alloHCT IL-33 administration expands recipient T-regulatory cells that protect mice against acute GVHD
Published Date
Jul 21, 2016
Journal
Volume
128
Issue
3
Pages
427 - 439
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Notes
History