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National Screening Committee’s criteria for appraising the viability, effectiveness and appropriateness of a screening programme

Published on Apr 1, 2014
Henry C Kitchener62
Estimated H-index: 62
,
Karen Canfell26
Estimated H-index: 26
+ 4 AuthorsJulian Peto4
Estimated H-index: 4
Abstract
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  • Citations (32)
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#1Paul M. Speight (University of Sheffield)H-Index: 52
Oral cancer is a serious health problem and appears to be amenable to screening. The oral cavity is easy to examine, and studies have shown that healthcare workers can detect oral potentially malignant lesions with a sensitivity and specificity similar to that found to be acceptable in other screening programs. However, there remain considerable barriers to the implementation of screening programs. The criteria for a positive test may not detect the lesions that are most likely to be malignant o...
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3 CitationsSource
#1Patrick A. TullyH-Index: 1
#2Ben A. Edwards (John Radcliffe Hospital)H-Index: 1
Last. Jayaratnam Jayamohan (John Radcliffe Hospital)H-Index: 12
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Background Idiopathic scoliosis is a relatively common childhood condition affecting 0.47–5.2% of the population. Traditional interventions focus on orthopaedic correction of the curve angle. There is a spectrum of patients with scoliosis who are found to have neuro-axial abnormality on full MRI of the spine, but not all surgeons request imaging in the absence of neurological symptoms. There is evidence to suggest that treatment of neuro-axial disease may improve scoliosis curve outcome. We ther...
2 CitationsSource
#1Andy Bilson (UCLan: University of Central Lancashire)H-Index: 9
This review of the 91 English children's services departments with specific policies on bruising in premobile children found a major disjuncture between research evidence and its interpretation in guidance. Many policies require all premobile children found with a bruise to be seen urgently by a paediatrician, and in some, all bruised children are subject of a formal child protection investigation regardless of the explanations for the bruise or the views of front‐line practitioners. However, th...
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Purpose of review There is a pressing need for effective strategies to halt the increase in both the incidence and mortality of esophageal adenocarcinoma (EAC). Screening for Barrett’s esophagus, which is the only known precursor of EAC, remains a ripe area for research, particularly with regard to identifying the target population, screening tools, and management of screen-detected populations. This review aims to explore in depth the rationale for screening for Barrett’s esophagus, recent biot...
2 CitationsSource
#1Laura J. GrayH-Index: 63
#2Andrew WillisH-Index: 5
Last. Kamlesh KhuntiH-Index: 4
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#1Angus John Clarke (Cardiff University)H-Index: 48
The genetically determined cardiomyopathies and arrhythmias are usually inherited as autosomal dominant traits with a wide range of inter- and intra-familial clinical variability concerning age at onset, penetrance, degree of symptoms and risk of cardiac death. In addition they are all characterized by extensive genetic and allelic heterogeneity. It has become obvious that molecular testing in clinical practice has an important impact on the management of patients and their families. With the in...
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#1Felicity K. Boardman (Warw.: University of Warwick)H-Index: 11
#2Chloe Sadler (Warw.: University of Warwick)H-Index: 1
Last. Philip J. Young (Warw.: University of Warwick)H-Index: 4
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Background: Spinal muscular atrophy (SMA) is an inherited neuromuscular disorder and a leading genetic cause of infant death worldwide. However, there is no routinescreening programme for SMA in the UK. Lack of treatments, and the inability of the screening test to accurately predict disease severity are among the key reasons screening programmes have faltered in the UK. With the recent release of the first therapy for SMA (Nusinersen) calls are being made for a reconsideration of this stance, h...
5 CitationsSource
#1Grace C. Cooper (University Hospital of South Manchester NHS Foundation Trust)H-Index: 1
#2Michelle Harvie (University Hospital of South Manchester NHS Foundation Trust)H-Index: 24
Last. David P. French (University of Manchester)H-Index: 42
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Purpose It has been suggested that receiving a negative screening test result may cause false reassurance or have a ‘certificate of health effect’. False reassurance in those receiving a negative screening test result may result in them wrongly believing themselves to be at lower risk of the disease, and consequently less likely to engage in health-related behaviours that would lower their risk. Methods The present systematic review aimed to identify the evidence regarding false reassurance effe...
5 CitationsSource
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