Response of Steroid-Refractory Acute GVHD to α 1 -Antitrypsin
Volume: 22, Issue: 9, Pages: 1596 - 1601
Published: Sep 1, 2016
Abstract
α1-Antitrypsin (AAT) is a serine protease inhibitor with anti-inflammatory, antiapoptotic, and immunomodulatory properties. It has therapeutic efficacy in animal models of autoimmune diseases, inflammatory disorders, and transplantation. In a phase I/II open-label single-center study, we administered AAT (Glassia; Baxalta/Kamada, New Ziona, Israel) as salvage therapy to 12 patients with steroid-refractory acute graft-versus-host disease (GVHD)....
Paper Details
Title
Response of Steroid-Refractory Acute GVHD to α 1 -Antitrypsin
Published Date
Sep 1, 2016
Volume
22
Issue
9
Pages
1596 - 1601
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