Ageing and the pathogenesis of osteoarthritis
Abstract
Ageing-associated changes that affect articular tissues promote the development of osteoarthritis (OA). Although ageing and OA are closely linked, they are independent processes. Several potential mechanisms by which ageing contributes to OA have been elucidated. This Review focuses on the contributions of the following factors: age-related inflammation (also referred to as 'inflammaging'); cellular senescence (including the...
Paper Details
Title
Ageing and the pathogenesis of osteoarthritis
Published Date
May 19, 2016
Journal
Volume
12
Issue
7
Pages
412 - 420
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History