Original paper
Syntheses and Anticancer Activities of Glycine Derivatives of Chrysin
Abstract
In order to obtain novel lead compounds with high efficacy,low toxicity and minimum of side effects,using chrysin(5,7-dihydroxyflavone) with very broad biological activities as a starting material,four intermediates 7-O-carboxyalkylation chrysin derivatives(6—9) were synthesized by halogenation and hydrolysis.Four glycine methyl ester derivatives containing chrysin(12—15) were synthesized when the four intermediates above condensated with...
Paper Details
Title
Syntheses and Anticancer Activities of Glycine Derivatives of Chrysin
Published Date
Jan 1, 2014
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