β_3-adrenergic receptor gene missense mutation is not related with simple obesity

AIM: To study the relationship between 3 adrenergic receptor (β 3AR) gene missense mutation and the simple obesity. METHODS: The β 3 adrenergic receptor gene was screened for nucleotide variations in the control subjects and cases of simple obesity. T→C missense mutation was determined by polymerase chain reaction restriction fragment length polymorphism (PCR RFLP) and serum concentration of triglyceride, total cholesterol, low density...