Population structure analysis on 2504 individuals across 26 ancestries using bioinformatics approaches
Abstract
Background Characterizing genetic diversity is crucial for reconstructing human evolution and for understanding the genetic basis of complex diseases; however, human population genetics are very complicated. Previously, we proved that based on the Hardy-Weinberg equilibrium, the heterozygous vs. non-reference homozygous single nucleotide polymorphism (SNP) ratio (het/nonref-hom) is two [1]. Later, we found that this ratio is race dependent, with...
Paper Details
Title
Population structure analysis on 2504 individuals across 26 ancestries using bioinformatics approaches
Published Date
Oct 23, 2015
Journal
Volume
16
Issue
S15
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Notes
History