Synthesis and Anticancer Activities of Derivatives Chrysin Derivatives

Objective To synthetize a variety of chrysin derivatives and identify their antitumor activity in vitro. Methods Chrysin was applied as main raw materials and the 5-Bromosalicylic acid ester was added to the reaction system to synthesize chrysin derivatives in the etherification reaction. Then the MTT method was used to detect the anticancer activities of chrysin derivatives on human gastric cell line MGC-803 and human hepatocellular carcimoma...