Segregated Delivery ofRifampicin and Isoniazid fromFixedDose Combination Bilayer Tabletsfor theTreatment ofTuberculosis
Published: Jan 1, 2014
Abstract
Aims: Develop an anti-tuberculosis (TB) Fixed Dose Combination (FDC) tablet containing an immediate release layer (IRL) composed of both rifampicin (RIF) and pyrazinamide (PYR) and a retarded release layer (RRL) comprised of isoniazid (INH) which would allow segregated delivery of RIF and INH. Study Design:Trialswere conducted on thepre-formulations andformulationsto assess the compatibilityof excipientsand obtain amodified release profile , for...
Paper Details
Title
Segregated Delivery ofRifampicin and Isoniazid fromFixedDose Combination Bilayer Tabletsfor theTreatment ofTuberculosis
Published Date
Jan 1, 2014
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