[Effect of arctiin on mouse podocyte epithelial-mesenchymal transition induced by advanced oxidation protein products].

To study the effect of arctiin on mouse podocyte epithelial-mesenchymal transition (EMT) induced by advanced oxidation protein products (AOPP).Mouse podocytes were stimulated by 200 µg/ml AOPP for 24 h in the presence of 50, 100, 200, and 400 µmol/L arctiin. The expressions of α-smooth muscle actin, Grp78 and CHOP were detected using Western blotting.The expressions of α-SMA, Grp78 and CHOP were inhibited by arctiin, showing a dose-dependent...