Resting-state fMRI study on alteration of amplitude of low frequency fluctuation and its relationship with aggressive behaviors in first-episode major depressive disorder patients

Objective To investigate the alterations of the amplitude of low frequency fluctuation(ALFF)by the restingstate fMRI in first-episode major depressive disorder(MDD)patients,and to analyze the relationship between brain area of different ALFF alterations with their aggressive behaviors.Methods Thirty first-episode MDD patients receiving no treatment or stopping treatment for 2weeks and 30sex-,age-,and education-matched healthy controls were...