Sequelae of hypergastrinemia due to long-term administration of proton pump inhibitors and its management

Abstract
Proton pump inhibitor (PPI) is considered as the standard treatment for acid-related disorders. However, its long-term use, especially in patients with gastroesophageal reflux disease, would cause potential risks, such as hypergastrinemia along with reduced gastric acidity, hyperplasia of enterochromaffin cells (ECL), gastric neoplasms, rebound gastric acid hypersecretion when PPI treatment is stopped, increased oxyntic gastritis in patients...
Paper Details
Title
Sequelae of hypergastrinemia due to long-term administration of proton pump inhibitors and its management
Published Date
Jan 1, 2006
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