[The effect of single nucleotide polymorphism SNP + 45 of the adiponectin gene on the rosiglitazone maleate response in patients with type 2 diabetes].

To investigate the effect of single nucleotide polymorphism (SNP) + 45 of the adiponectin (ADIPOQ) gene on the response to therapy with rosiglitazone maleate in patients with type 2 diabetes.A total of 103 newly diagnosed type 2 diabetes patients without taking any drug were enrolled and treated with rosiglitazone maleate (4 or 8 mg/d) for 24 weeks. On scheduled time phenotype measured were height, weight, waist, hip; blood pressure; HbA1c;...