Label-free fluorescent assay for high sensitivity and selectivity detection of acid phosphatase and inhibitor screening

In this work, we developed a convenient and label-free fluorescence sensing platform for sensitive detection of acid phosphatase (ACP) and its inhibitor. The selectivity fluorescent strategy was based on fluorescence enhancement mode of cysteamine-capped CdTe quantum dots (QDs). Upon addition of adenosine triphosphate (ATP), the amino groups on the surface of CdTe QDs can form both electrostatic and hydrogen bonding with ATP, leading to obvious...