Effect of therapeutic hypothermia on chromosomal aberration in perinatal asphyxia

Perinatal asphyxia is a major cause for neonatal mortality and morbidity around the world. The reduction of O2 results in the generation of reactive oxygen species which interact with nucleic acid and make alteration in the structure and functioning of the genome. We studied the effect of therapeutic hypothermia on chromosomes with karyotyping.Babies in the hypothermia group were cooled for the first 72 h, using gel packs. Rectal temperature of...