CRISPR/Cas9: Implications for Modeling and Therapy of Neurodegenerative Diseases
Abstract
CRISPR/Cas9 is now used widely to genetically modify the genomes of various species. The ability of CRISPR/Cas9 to delete DNA sequences and correct DNA mutations opens up a new avenue to treat genetic diseases that are caused by DNA mutations. In this review, we describe the advantages of using CRISPR/Cas9 to engineer genomic DNAs in animal embryos, as well as in specific regions or cell types in the brain. We also discuss how to apply...
Paper Details
Title
CRISPR/Cas9: Implications for Modeling and Therapy of Neurodegenerative Diseases
Published Date
Apr 28, 2016
Volume
9
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