Multiple functions of p21 in cell cycle, apoptosis and transcriptional regulation after DNA damage.

Volume: 42, Issue: 42, Pages: 63 - 71
Published: Jun 1, 2016
Abstract
An appropriate control over cell cycle progression depends on many factors. Cyclin-dependent kinase (CDK) inhibitor p21 (also known as p21(WAF1/Cip1)) is one of these factors that promote cell cycle arrest in response to a variety of stimuli. The inhibitory effect of P21 on cell cycle progression correlates with its nuclear localization. P21 can be induced by both p53-dependent and p53-independent mechanisms. Some other important functions...
Paper Details
Title
Multiple functions of p21 in cell cycle, apoptosis and transcriptional regulation after DNA damage.
Published Date
Jun 1, 2016
Journal
Volume
42
Issue
42
Pages
63 - 71
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