Amyloid β accumulation and inner retinal degenerative changes in Alzheimer's disease transgenic mouse.

Volume: 623, Pages: 52 - 56
Published: Jun 3, 2016
Abstract
The APP-PS1ΔE9 mouse model of Alzheimer’s disease (AD) exhibits age dependent amyloid β (Aβ) plaque formation in their central nervous system due to high expression of mutated human APP and PSEN1 transgenes. Here we evaluated Aβ deposition and changes in soluble Aβ accumulation in the retinas of aged APP-PS1 mice using a combination of immunofluorescence, retinal flat mounts and western blotting techniques. Aβ accumulation in the retina has...
Paper Details
Title
Amyloid β accumulation and inner retinal degenerative changes in Alzheimer's disease transgenic mouse.
Published Date
Jun 3, 2016
Volume
623
Pages
52 - 56
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