Mo1232 The Helicobacter Eradication Aspirin Trial (HEAT): A Large Simple Randomised Controlled Trial Using Novel Methodology in Primary Care

Introduction null Clinical trials measuring the effect of an intervention on clinical outcomes are more influential than those investigating surrogate measures but are costly. We developed methods to reduce costs substantially by using existing data in primary and secondary care systems, to ask whether null Helicobacter pylori eradication would reduce the incidence of hospitalisation for ulcer bleeding in aspirin users. null Method null The null...