Aging: A Temporal Dimension for Neutrophils

Acute inflammatory syndromes, as well as other types of disease, show circadian patterns of manifestation that parallel changes in the number of circulating leukocytes. Neutrophils are the most abundant myeloid cells in blood, and their numbers follow circadian patterns of release and clearance. Neutrophils undergo phenotypic changes from the time they are released into blood (fresh neutrophils) to the time they disappear from the circulation...