CTCF and Cohesin in Genome Folding and Transcriptional Gene Regulation

Volume: 17, Issue: 1, Pages: 17 - 43
Published: Aug 31, 2016
Abstract
Genome function, replication, integrity, and propagation rely on the dynamic structural organization of chromosomes during the cell cycle. Genome folding in interphase provides regulatory segmentation for appropriate transcriptional control, facilitates ordered genome replication, and contributes to genome integrity by limiting illegitimate recombination. Here, we review recent high-resolution chromosome conformation capture and functional...
Paper Details
Title
CTCF and Cohesin in Genome Folding and Transcriptional Gene Regulation
Published Date
Aug 31, 2016
Volume
17
Issue
1
Pages
17 - 43
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