Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma
Abstract
Large-scale genomic characterization of tumors from prospective cohort studies may yield new insights into cancer pathogenesis. We performed whole-exome sequencing of 619 incident colorectal cancers (CRCs) and integrated the results with tumor immunity, pathology, and survival data. We identified recurrently mutated genes in CRC, such as BCL9L, RBM10, CTCF, and KLF5, that were not previously appreciated in this disease. Furthermore, we...
Paper Details
Title
Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma
Published Date
Apr 26, 2016
Journal
Volume
15
Issue
4
Pages
857 - 865
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