Donor-Specific Anti-HLA Antibodies of Immunoglobulin G3 Subclass Correlate with Cellular Rejection after Cardiac Transplantation

HLA donor-specific antibodies (DSAs) of immunoglobulin (IgG) type are associated with antibody-mediated rejection. Aim of this study was to determine if the IgG subtype was associated with cellular rejection in patients who underwent cardiac transplantation at a pediatric center. Serum samples were obtained in conjunction with endomyocardial biopsies (EMB), which were graded for cellular rejection. DSAs were identified by single-antigen beads...