Reduced habituation of auditory evoked potentials indicate cortical hyper-excitability in Fragile X Syndrome
Abstract
Sensory hypersensitivities are common, clinically distressing features of Fragile X Syndrome (FXS). Preclinical evidence suggests this abnormality may result from synaptic hyper-excitability in sensory systems. This model predicts reduced sensory habituation to repeated stimulus presentation. Fourteen adolescents and adults with FXS and 15 age-matched controls participated in a modified auditory gating task using trains of 4 identical tones...
Paper Details
Title
Reduced habituation of auditory evoked potentials indicate cortical hyper-excitability in Fragile X Syndrome
Published Date
Apr 19, 2016
Journal
Volume
6
Issue
4
Pages
e787 - e787
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