Thrombosis and von Willebrand Factor
Abstract
One of the key players in both hemostasis and thrombosis is von Willebrand factor (vWF), which demonstrates a duality between these two processes. Thrombus is structured by numerous elements, including endothelial cells, platelets, plasma proteins and shear stress alteration. In circulation, once a vessel wall is injured, collagen is exposed and platelets attach to the site of injury. Accordingly, vWF mediates adherence of platelets to the...
Paper Details
Title
Thrombosis and von Willebrand Factor
Published Date
Jan 1, 2016
Pages
285 - 306
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