Marker of endothelial dysfunction may improve the early detection of insulin resistance and subclinical atherosclerosis

Published on Dec 1, 2015in Diabetology & Metabolic Syndrome 2.41
· DOI :10.1186/1758-5996-7-S1-A113
Bianca de Almeida Pititto1
Estimated H-index: 1
(Federal University of São Paulo),
Fernando Flexa Ribeiro Filho8
Estimated H-index: 8
(Federal University of São Paulo)
+ 3 AuthorsSandra R.G. Ferreira18
Estimated H-index: 18
(Federal University of São Paulo)
Abstract
Materials and methods A sample of 998 individuals from the ELSA-Brazil (35-54 yrs.) without cardiovascular disease or diabetes was stratified according to E-selectin tertiles. Traditional risk factors, inflammatory markers and categories of coronary artery calcium (CAC) score were evaluated across the tertiles by ANOVA or chi-squared test. In linear regression models, associations of E-selectin levels with insulin resistance index, adjusted for age, sex and adiposity were tested.
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Published on Jan 1, 2016in Amino Acids 2.91
Caroline B. Quines6
Estimated H-index: 6
(Universidade Federal de Santa Maria),
Suzan Gonçalves Rosa7
Estimated H-index: 7
(Universidade Federal de Santa Maria)
+ 6 AuthorsCristina W. Nogueira50
Estimated H-index: 50
(Universidade Federal de Santa Maria)
The metabolic syndrome is a group of metabolic alterations considered a worldwide public health problem. Organic selenium compounds have been reported to have many different pharmacological actions, such as anti-hypercholesterolemic and anti-hyperglycemic. The aim of this study was to evaluate the effect of p-chloro-diphenyl diselenide (p-ClPhSe)2, an organic selenium compound, in a model of obesity induced by monosodium glutamate (MSG) administration in rats. The rats were treated during the fi...
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