Original paper
Investigating Various Thresholds as Immunohistochemistry Cutoffs for Observer Agreement
Volume: 25, Issue: 9, Pages: 599 - 608
Published: Oct 1, 2017
Abstract
Background: Clinical translation of immunohistochemistry (IHC) biomarkers requires reliable and reproducible cutoffs or thresholds for interpretation of immunostaining. Most IHC biomarker research focuses on the clinical relevance (diagnostic, prognostic, or predictive utility) of cutoffs, with less emphasis on observer agreement using these cutoffs. From the literature, we identified 3 commonly used cutoffs of 10% positive epithelial cells, 20%...
Paper Details
Title
Investigating Various Thresholds as Immunohistochemistry Cutoffs for Observer Agreement
Published Date
Oct 1, 2017
Volume
25
Issue
9
Pages
599 - 608
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