Safety and completion of a 4-month course of rifampicin for latent tuberculous infection in children

Children's Tuberculosis Clinic, Houston, Texas.To describe adherence to and tolerability of 4 months of rifampicin (4RMP) compared to 9 months of isoniazid (9INH) in children with latent tuberculous infection (LTBI).Retrospective descriptive case series of children treated for LTBI from 2010 to 2013 by self-administered therapy or directly observed preventive therapy (DOPT) administered by the local health department.Four hundred and four...