Proteomic and Phosphoproteomic Analysis of Chicken Embryo Fibroblasts Infected with Cell Culture-Attenuated and Vaccine Strains of Marek’s Disease Virus

Vaccination is an effective strategy to reduce the loss of chickens in the poultry industry caused by Marek’s Disease (MD), an avian lymphoproliferative disease. The vaccines currently used are from attenuated serotype 1 Marek’s disease virus (MDV) or naturally nononcogenic MDV strains. To prepare for future immunity breaks, functional genomic and proteomic studies have been used to better understand the underlying mechanisms of MDV...