Increased level of circulating U2 small nuclear RNA fragments indicates metastasis in melanoma patients
Abstract
Melanoma is the most aggressive skin cancer and, despite recent advances in therapy, about 20% of the patients die of their disease. Early relapse detection and monitoring of therapy response are crucial for efficient treatment of advanced melanoma. Thus, there is a need for blood-based biomarkers in melanoma management. Serum-derived U2 small nuclear RNA fragments (RNU2-1f) were previously shown to be blood-based biomarkers for gastrointestinal...
Paper Details
Title
Increased level of circulating U2 small nuclear RNA fragments indicates metastasis in melanoma patients
Published Date
Jan 1, 2015
Volume
53
Issue
4
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