Mesenteric Adipocyte Dysfunction in Crohnʼs Disease is Associated with Hypoxia

Abnormalities in mesenteric adipose tissue (MAT) have long been recognized; however, the functional changes in the mesenteric adipocytes as well as the underlying mechanisms are not entirely clear. The aim of this study was to analyze the function and morphology of the MAT in patients with Crohn's disease (CD) and the underlying mechanism.The MAT specimens were obtained from areas adjacent to the intestinal wall in patients with CD (n = 33) and...