Suppression of EC-SOD by oxLDL During Vascular Smooth Muscle Cell Proliferation
Volume: 117, Issue: 11, Pages: 2496 - 2505
Published: Apr 1, 2016
Abstract
Reactive oxygen species (ROS) produced by endothelial cells and macrophages play important roles in atherogenesis because they promote the formation of oxidized low-density lipoproteins (oxLDL). Extracellular-superoxide dismutase (EC-SOD) is mainly produced by vascular smooth muscle cells (VSMCs), is secreted into the extracellular space, and protects cells from the damaging effects of the superoxide anion. Thus, the expression of EC-SOD in...
Paper Details
Title
Suppression of EC-SOD by oxLDL During Vascular Smooth Muscle Cell Proliferation
Published Date
Apr 1, 2016
Volume
117
Issue
11
Pages
2496 - 2505
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