Biochemical Variation Among Normal Equine Carpal and Tarsocrural Joint Fluids are Detected by Infrared Spectral Characteristics and A Modified Approach to Linear Discriminant Analysis

Research into osteoarthritis diagnostics has evolved from traditional methods that are only useful in more advanced clinical disease, towards the discovery of biomarkers that are predictive or reflective of preclinical joint disease. The potential of Fourier transform infrared spectroscopy (FTIR) coupled with chemometrics has been demonstrated as useful for the assessment of biomolecular responses to disease. Joint fluid was collected from 105...