Adipose Insulin Resistance in Obese Adolescents Across the Spectrum of Glucose Tolerance

Adipocytes represent an important insulin-responsive tissue taking an active part in glucose metabolism. This study sought to assess adipose tissue insulin resistance (IR) across the spectrum of glucose tolerance and to test its relation with free fatty acid (FFA) suppression during an oral glucose tolerance test (OGTT). A cross-sectional analysis of a pediatric clinic–derived cohort of obese adolescents. Participants age 7–20 y with a body mass...