Intervention to Prevent Major Depression in Primary Care

Not enough is known about universal prevention of depression in adults.To evaluate the effectiveness of an intervention to prevent major depression.Multicenter, cluster randomized trial with sites randomly assigned to usual care or an intervention. (ClinicalTrials.gov: NCT01151982).10 primary care centers in each of 7 cities in Spain.Two primary care physicians (PCPs) and 5236 nondepressed adult patients were randomly sampled from each center;...