Latent Cytomegalovirus Infection in Rheumatoid Arthritis and Increased Frequencies of Cytolytic LIR‐1+CD8+ T Cells

Volume: 68, Issue: 2, Pages: 337 - 346
Published: Jan 25, 2016
Abstract
Leukocyte immunoglobulin-like receptor 1 (LIR-1) is up-regulated by cytomegalovirus (CMV), which in turn, has been associated with premature aging and more severe joint disease in patients with rheumatoid arthritis (RA). The aim of this study was to investigate the expression and functional significance of LIR-1 in CMV-positive RA patients.We determined the phenotype, cytolytic potential, CMV-specific proliferation, and HLA-G-triggered,...
Paper Details
Title
Latent Cytomegalovirus Infection in Rheumatoid Arthritis and Increased Frequencies of Cytolytic LIR‐1+CD8+ T Cells
Published Date
Jan 25, 2016
Volume
68
Issue
2
Pages
337 - 346
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