Splice form variant and amino acid changes in MDR49 confers DDT resistance in transgenic Drosophila

Volume: 6, Issue: 1
Published: Mar 22, 2016
Abstract
The ATP-binding cassette (ABC) transporters represent a superfamily of proteins that have important physiological roles in both prokaryotes and eukaryotes. In insects, ABC transporters have previously been implicated in insecticide resistance. The 91-R strain of Drosophila melanogaster has been intensely selected with DDT over six decades. A recent selective sweeps analysis of 91-R implicated the potential role of MDR49, an ABC transporter, in...
Paper Details
Title
Splice form variant and amino acid changes in MDR49 confers DDT resistance in transgenic Drosophila
Published Date
Mar 22, 2016
Volume
6
Issue
1
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