Introducing precise genetic modifications into human 3PN embryos by CRISPR/Cas-mediated genome editing

Published on May 1, 2016in Journal of Assisted Reproduction and Genetics2.82
· DOI :10.1007/s10815-016-0710-8
Xiangjin Kang6
Estimated H-index: 6
(Guangzhou Medical University),
Wenyin He7
Estimated H-index: 7
(Guangzhou Medical University)
+ 5 AuthorsYong Fan12
Estimated H-index: 12
(Guangzhou Medical University)
Purpose As a powerful technology for genome engineering, the CRISPR/Cas system has been successfully applied to modify the genomes of various species. The purpose of this study was to evaluate the technology and establish principles for the introduction of precise genetic modifications in early human embryos.
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