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Introducing precise genetic modifications into human 3PN embryos by CRISPR/Cas-mediated genome editing

Published on May 1, 2016in Journal of Assisted Reproduction and Genetics2.82
· DOI :10.1007/s10815-016-0710-8
Xiangjin Kang6
Estimated H-index: 6
(Guangzhou Medical University),
Wenyin He7
Estimated H-index: 7
(Guangzhou Medical University)
+ 5 AuthorsYong Fan12
Estimated H-index: 12
(Guangzhou Medical University)
Abstract
Purpose As a powerful technology for genome engineering, the CRISPR/Cas system has been successfully applied to modify the genomes of various species. The purpose of this study was to evaluate the technology and establish principles for the introduction of precise genetic modifications in early human embryos.
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  • References (40)
  • Citations (118)
References40
Newest
#1Puping Liang (SYSU: Sun Yat-sen University)H-Index: 7
#2Yanwen Xu (SYSU: Sun Yat-sen University)H-Index: 14
Last.Junjiu Huang (SYSU: Sun Yat-sen University)H-Index: 18
view all 16 authors...
#1David Baltimore (California Institute of Technology)H-Index: 173
#2Paul Berg (Stanford University)H-Index: 73
Last.Marsha Fenner (University of California, Berkeley)H-Index: 1
view all 18 authors...
#1Daesik Kim (SNU: Seoul National University)H-Index: 12
#2Sangsu Bae (Hanyang University)H-Index: 13
Last.Jinsoo Kim (SNU: Seoul National University)H-Index: 49
view all 9 authors...
#1Chen YuH-Index: 10
#2Yanxia Liu (Stanford University)H-Index: 13
Last.Sheng Ding (UCSF: University of California, San Francisco)H-Index: 59
view all 11 authors...
#1Shengdar Q. Tsai (Harvard University)H-Index: 24
#2Zongli Zheng (KI: Karolinska Institutet)H-Index: 24
Last.Long P. Le (Harvard University)H-Index: 19
view all 12 authors...
#1Chengzu Long (UTSW: University of Texas Southwestern Medical Center)H-Index: 17
#2John R. McAnally (UTSW: University of Texas Southwestern Medical Center)H-Index: 17
Last.Eric N. Olson (UTSW: University of Texas Southwestern Medical Center)H-Index: 182
view all 6 authors...
Cited By118
Newest
#1Yagiz Aksoy (Macquarie University)H-Index: 1
#2David T. Nguyen (Garvan Institute of Medical Research)H-Index: 1
Last.Daniel Hesselson (UNSW: University of New South Wales)H-Index: 14
view all 7 authors...
#1Guanglei Li (Guangzhou Medical University)H-Index: 4
#2Xinyi Liu (JNU: Jinan University)
Last.Xingxu Huang (CAS: Chinese Academy of Sciences)H-Index: 14
view all 11 authors...
#1Tania Bubela (SFU: Simon Fraser University)H-Index: 2
#2Erika Kleiderman (McGill University)H-Index: 5
Last.Bartha Maria Knoppers (McGill University)H-Index: 49
view all 7 authors...
#1Yanni Li (Guangzhou Medical University)
#2Xiang Jin Kang (Guangzhou Medical University)H-Index: 1
Last.Yong Fan (Guangzhou Medical University)H-Index: 12
view all 6 authors...
#1Rafael Nogueira Furtado (PUC-SP: Pontifícia Universidade Católica de São Paulo)
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