Tumor angiogenesis and metastasis--correlation in invasive breast carcinoma.
Abstract
Background. Experimental evidence suggests that the growth of a tumor beyond a certain size requires angiogenesis, which may also permit metastasis. To investigate how tumor angiogenesis correlates with metastases in breast carcinoma, we counted microvessels (capillaries and venules) and graded the density of microvessels within the initial invasive carcinomas of 49 patients (30 with metastases and 19 without). Methods. Using light microscopy,...
Paper Details
Title
Tumor angiogenesis and metastasis--correlation in invasive breast carcinoma.
Published Date
Jan 3, 1991
Volume
324
Issue
1
Pages
1 - 8
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