Synthetic Analogues of Nickel Superoxide Dismutase: A New Role for Nickel in Biology
Abstract
Nickel-containing superoxide dismutases (NiSODs) represent a novel approach to the detoxification of superoxide in biology and thus contribute to the biodiversity of mechanisms for the removal of reactive oxygen species (ROS). While Ni ions play critical roles in anaerobic microbial redox (hydrogenases and CO dehydrogenase/acetyl coenzyme A synthase), they have never been associated with oxygen metabolism. Several SODs have been characterized...
Paper Details
Title
Synthetic Analogues of Nickel Superoxide Dismutase: A New Role for Nickel in Biology
Published Date
Dec 26, 2012
Journal
Volume
52
Issue
1
Pages
4 - 18
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